This work provides a hypothesis of evolutionary relationships within the Neotropical genus Sparganothina and between this genus and other lineages of Sparganothini (Lepidoptera: Tortricidae). Nineteen species are considered to belong to Sparganothina. Ten additional species are placed in "Sparganothina" and five in "Coelostathma" pending a better phylogenetic understanding of Coelostathma and related genera. Thirty species are described as new.